Anti-USP30 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-USP30 Polyclonal Antibody
中文名称： 泛素特异性肽酶30抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Mouse
应用： WB
稀释比例： WB 1:1000-3000.

抗体信息

靶标： USP30
别名： Deubiquitinating enzyme 30, FLJ40511, Ub-specific protease 30, Ubiquitin carboxyl terminal hydrolase 30, Ubiquitin carboxyl-terminal hydrolase 30, Ubiquitin specific peptidase 30, Ubiquitin specific processing protease 30, Ubiquitin thioesterase 30, Ubiquitin thiolesterase 30, Ubiquitin-specific-processing protease 30, UBP30_HUMAN, usp30
背景说明： Deubiquitinating enzyme tethered to the mitochondrial outer membrane that acts as a key inhibitor of mitophagy by counteracting the action of parkin (PRKN): hydrolyzes ubiquitin attached by parkin on target proteins, such as RHOT1/MIRO1 and TOMM20, thereby blocking parkin's ability to drive mitophagy (PubMed:18287522, PubMed:24896179, PubMed:25527291, PubMed:25621951). Preferentially cleaves 'Lys-6'- and 'Lys-11'-linked polyubiquitin chains, 2 types of linkage that participate in mitophagic signaling (PubMed:25621951). Does not cleave efficiently polyubiquitin phosphorylated at 'Ser-65' (PubMed:25527291). Acts as negative regulator of mitochondrial fusion by mediating deubiquitination of MFN1 and MFN2 (By similarity).
Swiss Prot： Q70CQ3
Gene ID： 84749
亚细胞定位： Cytoplasm
免疫原： Recombinant protein of human USP30
Public Immunogen Range： 91-420aa
理论分子量： 59kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。