Anti-HIF1AN Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-HIF1AN Polyclonal Antibody
中文名称： 缺氧诱导因子1,α亚单位抑制剂抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Rat ; Mouse
应用： WB ; IHC ; IF
稀释比例： WB 1:1000-3000. IHC 1:50-200. IF 1:50-200.

抗体信息

靶标： HIF1AN
别名： Hypoxia inducible factor asparagine hydroxylase, Factor inhibiting HIF1, FIH 1, FIH-1, FIH1, Hypoxia inducible factor 1 alpha inhibitor, Hypoxia inducible factor 1 alpha subunit inhibitor, Peptide aspartate beta dioxygenase, DKFZp762F1811, FLJ20615, FLJ22027, HIF1N_HUMAN
背景说明： Hydroxylates HIF-1 alpha at 'Asn-803' in the C-terminal transactivation domain (CAD). Functions as an oxygen sensor and, under normoxic conditions, the hydroxylation prevents interaction of HIF-1 with transcriptional coactivators including Cbp/p300-interacting transactivator. Involved in transcriptional repression through interaction with HIF1A, VHL and histone deacetylases. Hydroxylates specific Asn residues within ankyrin repeat domains (ARD) of NFKB1, NFKBIA, NOTCH1, ASB4, PPP1R12A and several other ARD-containing proteins. Also hydroxylates Asp and His residues within ARDs of ANK1 and TNKS2, respectively. Negatively regulates NOTCH1 activity, accelerating myogenic differentiation. Positively regulates ASB4 activity, promoting vascular differentiation.
Swiss Prot： Q9NWT6
Gene ID： 55662
亚细胞定位： Nucleus Cytoplasm
免疫原： Recombinant protein of human HIF1AN
Public Immunogen Range： 1-350aa
理论分子量： 40kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。