Anti-VPS11 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-VPS11 Polyclonal Antibody
中文名称： 液泡蛋白分拣蛋白11抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Mouse
应用： IHC
稀释比例： IHC 1:100-300.

抗体信息

靶标： VPS11
别名： END1, HGNC:14583, hVPS11, PEP5, PP3476, RING finger protein 108, RNF108, Vacuolar protein sorting 11 (yeast homolog), Vacuolar protein sorting 11 (yeast), Vacuolar protein sorting 11 homolog (S. cerevisiae), Vacuolar protein sorting 11 homolog, Vacuolar protein sorting associated protein 11 homolog, Vacuolar protein sorting protein 11, Vacuolar protein sorting-associated protein 11 homolog, vps11, VPS11_HUMAN
背景说明： Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes which are proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The HOPS complex is proposed to be recruited to Rab7 on the late endosomal membrane and to regulate late endocytic, phagocytic and autophagic traffic towards lysosomes. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations. Required for fusion of endosomes and autophagosomes with lysosomes. Involved in cargo transport from early to late endosomes and required for the transition from early to late endosomes. Involved in the retrograde Shiga toxin transport.
Swiss Prot： Q9H270
Gene ID： 55823
亚细胞定位： Cytoplasm
免疫原： Recombinant protein of Human VPS11
Public Immunogen Range： 1-331aa
理论分子量： 108kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
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注意事项 Considerations

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