Anti-PACSIN1 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-PACSIN1 Polyclonal Antibody
中文名称： 神经元蛋白激酶C酪蛋白激酶底物1抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Rat ; Mouse
应用： WB
稀释比例： WB 1:8000-12000.

抗体信息

靶标： PACSIN1
别名： PACSIN1,KIAA1379,Protein kinase C and casein kinase substrate in neurons protein 1,Syndapin-1
背景说明： Plays a role in the reorganization of the microtubule cytoskeleton via its interaction with MAPT; this decreases microtubule stability and inhibits MAPT-induced microtubule polymerization. Plays a role in cellular transport processes by recruiting DNM1, DNM2 and DNM3 to membranes. Plays a role in the reorganization of the actin cytoskeleton and in neuron morphogenesis via its interaction with COBL and WASL, and by recruiting COBL to the cell cortex. Plays a role in the regulation of neurite formation, neurite branching and the regulation of neurite length. Required for normal synaptic vesicle endocytosis; this process retrieves previously released neurotransmitters to accommodate multiple cycles of neurotransmission. Required for normal excitatory and inhibitory synaptic transmission (By similarity). Binds to membranes via its F-BAR domain and mediates membrane tubulation.
Swiss Prot： Q9BY11
Gene ID： 29993
亚细胞定位： Cytoplasm
免疫原： Recombinant protein of Human PACSIN1
Public Immunogen Range： 1-444aa
理论分子量： 51kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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