Anti-NF2 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-NF2 Polyclonal Antibody
中文名称： 神经纤维瘤蛋白2抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Rat ; Mouse
应用： IHC
稀释比例： IHC 1:100-300.

抗体信息

靶标： NF2
别名： neurofibromatosis type 2, CAN, BANF, bilateral acoustic neuroma, moesin ezrin radixin like protein, Moesin ezrin radizin like protein, merlin, Neurofibromatosis 2, ACN, Bilateral acoustic neuroma, MERL_HUMAN, Merlin, Moesin ezrin radizin like, Moesin-ezrin-radixin-like protein, Neurofibromatosis type 2, Neurofibromin-2, NF 2, Nf2, Neurofibromatosis2, Neurofibromin 2, Neurofibromin2, Schwannomerlin, NF-2, SCH, Schwannomin
背景说明： Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity. Suppresses cell proliferation and tumorigenesis by inhibiting the CUL4A-RBX1-DDB1-VprBP/DCAF1 E3 ubiquitin-protein ligase complex.
Swiss Prot： P35240
Gene ID： 4771
亚细胞定位： Cytoplasm
免疫原： A synthetic peptide of human NF2
Public Immunogen Range： 60-110/595aa
理论分子量： 73/70/69/65/64//59/30/25/19kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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