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Anti-SRSF1 Polyclonal Antibody,BR
Anti-SRSF1 Polyclonal Antibody
(订货以英文名为准)猜你喜欢
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产品属性 Product Attributes
基本信息
英文名称: Anti-SRSF1 Polyclonal Antibody中文名称: 剪接因子,精氨酸/丝氨酸丰富1抗体
规格: 50ul ; 100ul
宿主: Rabbit
克隆类型: Polyclonal Antibody
亚型: IgG
交叉反应:: Mouse ; Human预测
交叉反应:: Zebrafish;Cow
应用: WB ; IHC
稀释比例: WB 1:1000-3000. IHC 1:100-300.
抗体信息
靶标: SRSF1别名: ASF;SF2;SF2p33;SFRS1;SRp30a
背景说明: Plays a role in preventing exon skipping, ensuring the accuracy of splicing and regulating alternative splicing. Interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF. Can stimulate binding of U1 snRNP to a 5'-splice site-containing pre-mRNA. Binds to purine-rich RNA sequences, either the octamer, 5'-RGAAGAAC-3' (r=A or G) or the decamers, AGGACAGAGC/AGGACGAAGC. Binds preferentially to the 5'-CGAGGCG-3' motif in vitro. Three copies of the octamer constitute a powerful splicing enhancer in vitro, the ASF/SF2 splicing enhancer (ASE) which can specifically activate ASE-dependent splicing. Isoform ASF-2 and isoform ASF-3 act as splicing repressors. May function as export adapter involved in mRNA nuclear export through the TAP/NXF1 pathway.
Swiss Prot: Q07955
Gene ID: 6426
亚细胞定位: Nucleus
免疫原: A synthetic peptide of human SRSF1
Public Immunogen Range: 85-135/248aa
理论分子量: 22/28/32kDa
其它标识
纯化方法: Affinity purification储存液: PBS with 50% Glycerol,0.03% Proclin300,0.5% BSA,pH 7.3.
储存条件: Store at -20℃. Avoid freeze/thaw cycles.
产品介绍 Product Introduction
使用前请离心。如有问题请及时联系我们。Quick spin before use. If you have any questions, please contact us.
注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。
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