Anti-PTPN1 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-PTPN1 Polyclonal Antibody
中文名称： 非受体1型蛋白酪氨酸磷酸酶抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human
应用： WB
稀释比例： WB 1:1000-3000.

抗体信息

靶标： PTPN1
别名： PTP-1B, Non receptor tyrosine phosphatase 1, Protein tyrosine phosphatase 1B, Protein-tyrosine phosphatase 1B, Protein tyrosine phosphatase non receptor type 1, Protein tyrosine phosphatase placental, PTP 1B, PTPN 1, PTPN1, Tyrosine protein phosphatase non receptor type 1, PTP-HA2, Protein-tyrosine phosphatase HA2, PTN1_HUMAN
背景说明： The protein encoded by this gene is the founding member of the protein tyrosine phosphatase (PTP) family, which was isolated and identified based on its enzymatic activity and amino acid sequence. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP has been shown to act as a negative regulator of insulin signaling by dephosphorylating the phosphotryosine residues of insulin receptor kinase. This PTP was also reported to dephosphorylate epidermal growth factor receptor kinase, as well as JAK2 and TYK2 kinases, which implicated the role of this PTP in cell growth control, and cell response to interferon stimulation. Two transcript variants encoding different isoforms have been found for this gene.
Swiss Prot： P18031
Gene ID： 5770
亚细胞定位： Cytoplasm
免疫原： A synthetic peptide of human PTPN1
Public Immunogen Range： 335-385/435aa
理论分子量： 50kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。