Anti-MAPK8IP1 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-MAPK8IP1 Polyclonal Antibody
中文名称： 丝裂原活化蛋白激酶8相互作用蛋白1抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Mouse ; Human
应用： IHC
稀释比例： IHC 1:100-300.

抗体信息

靶标： MAPK8IP1
别名： C jun amino terminal kinase interacting protein 1, IB 1, IB1, Islet brain 1, JIP 1, JNK interacting protein 1, JNK MAP kinase scaffold protein 1, MAPK8IP 1, MAPK8IP1, Mitogen activated protein kinase 8 interacting protein 1, PRKM8 interacting protein, PRKM8IP, JIP1_HUMAN
背景说明： This gene encodes a regulator of the pancreatic beta-cell function. It is highly similar to JIP-1, a mouse protein known to be a regulator of c-Jun amino-terminal kinase (Mapk8). This protein has been shown to prevent MAPK8 mediated activation of transcription factors, and to decrease IL-1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells. This protein also functions as a DNA-binding transactivator of the glucose transporter GLUT2. RE1-silencing transcription factor (REST) is reported to repress the expression of this gene in insulin-secreting beta cells. This gene is found to be mutated in a type 2 diabetes family, and thus is thought to be a susceptibility gene for type 2 diabetes.
Swiss Prot： Q9UQF2
Gene ID： 9479
亚细胞定位： Cytoplasm Cell membrane Nucleus
免疫原： A synthetic peptide of human MAPK8IP1
Public Immunogen Range： 60-110/711aa
理论分子量： 78kDa

其它标识

纯化方法： Octanoic acid-ammonium sulfate precipitation
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。