Anti-CAV1 Polyclonal Antibody,BR

英文名称:Anti-CAV1 Polyclonal Antibody
宿主:Rabbit
别名:BSCL3;CGL3;LCCNS;MSTP085;PPH3;VIP21;Caveolin-1;CAV;
交叉反应:Human Mouse Rat
应用:WB
稀释比例:WB 1:1000-3000.
蛋白分子量:17/20kDa
Gene ID:857
保存:Store at -20°C. Avoid freeze / thaw cycles.
储存液:Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法:Affinity purification
亚型:IgG
免疫原:Recombinant protein of human CAV1
亚细胞定位:Cell membrane Cytoplasm
Swiss Prot:Q03135
背景资料:The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.
克隆类型:Polyclonal Antibody
规格:50ul, 100ul, 注意：
1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
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