Anti-ARPC1B Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-ARPC1B Polyclonal Antibody
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Rat ; Mouse预测
交叉反应：： Cow;Xenopus laevis
应用： IHC
稀释比例： IHC 1:50-200.

抗体信息

靶标： ARPC1B
别名： Actin related protein 2/3 complex subunit 1B 41kDa; Actin related protein 2/3 complex subunit 1B; Actin-related protein 2/3 complex subunit 1B; ARC1B_HUMAN; ARC41; Arp2/3 complex 41 kDa subunit; ARP2/3 protein complex subunit p41; Arpc1b; p40 ARC; p41 ARC; p41-Arc;
背景说明： Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:11741539, PubMed:9230079). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (PubMed:11741539, PubMed:9230079). In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (PubMed:29925947). The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs) (PubMed:29925947).
Swiss Prot： O15143
Gene ID： 10095
亚细胞定位： Cytoplasm
免疫原： A synthetic peptide of human ARPC1B
Public Immunogen Range： 322-372/372aa
理论分子量： 41kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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