Anti-RPRD1B Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-RPRD1B Polyclonal Antibody
中文名称： 肿瘤高表达细胞周期相关蛋白抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Mouse
应用： WB
稀释比例： WB 1:1000-3000.

抗体信息

靶标： RPRD1B
别名： C20orf77, Cell cycle related and expression elevated protein in tumor, Chromosome 20 open reading frame 77, CREPT, dJ1057B20.2, DKFZp434P0735, FLJ44520, Hypothetical protein LOC58490, Uncharacterized protein C20orf77, RPR1B_HUMAN
背景说明： Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD by RPAP2. Transcriptional regulator which enhances expression of CCND1. Promotes binding of RNA polymerase II to the CCDN1 promoter and to the termination region before the poly-A site but decreases its binding after the poly-A site. Prevents RNA polymerase II from reading through the 3' end termination site and may allow it to be recruited back to the promoter through promotion of the formation of a chromatin loop. Also enhances the transcription of a number of other cell cycle-related genes including CDK2, CDK4, CDK6 and cyclin-E but not CDKN1A, CDKN1B or cyclin-A. Promotes cell proliferation.
Swiss Prot： Q9NQG5
Gene ID： 58490
亚细胞定位： Nucleus
免疫原： A synthetic peptide of human RPRD1B
Public Immunogen Range： 55-105/326aa
理论分子量： 37kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。