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Anti-IFIT1 Polyclonal Antibody,BR
Anti-IFIT1 Polyclonal Antibody
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产品属性 Product Attributes
基本信息
英文名称: Anti-IFIT1 Polyclonal Antibody中文名称: 干扰素诱导的三角形四肽重复蛋白1抗体
规格: 50ul ; 100ul
宿主: Rabbit
克隆类型: Polyclonal Antibody
亚型: IgG
交叉反应:: Human
应用: WB
稀释比例: WB 1:1000-3000.
抗体信息
靶标: IFIT1别名: C56;G10P1;IFI-56;IFI-56K;IFI56;IFIT-1;IFNAI1;ISG56;P56;RNM561
背景说明: Interferon-induced antiviral RNA-binding protein that specifically binds single-stranded RNA bearing a 5'-triphosphate group (PPP-RNA), thereby acting as a sensor of viral single-stranded RNAs and inhibiting expression of viral messenger RNAs. Single-stranded PPP-RNAs, which lack 2'-O-methylation of the 5' cap and bear a 5'-triphosphate group instead, are specific from viruses, providing a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Directly binds PPP-RNA in a non-sequence-specific manner. Viruses evolved several ways to evade this restriction system such as encoding their own 2'-O-methylase for their mRNAs or by stealing host cap containing the 2'-O-methylation (cap snatching mechanism). Exhibits antiviral activity against several viruses including human papilloma and hepatitis C viruses.
Swiss Prot: P09914
Gene ID: 3434
亚细胞定位: Cytoplasm
免疫原: Recombinant protein of human IFIT1
Public Immunogen Range: 1-350aa
理论分子量: 52/55kDa
其它标识
纯化方法: Affinity purification储存液: PBS with 50% Glycerol,0.03% Proclin300,0.5% BSA,pH 7.3.
储存条件: Store at -20℃. Avoid freeze/thaw cycles.
产品介绍 Product Introduction
使用前请离心。如有问题请及时联系我们。Quick spin before use. If you have any questions, please contact us.
注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。