Anti-NCAPD2 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-NCAPD2 Polyclonal Antibody
中文名称： 非SMC凝缩蛋白I复合物亚基D2抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Rat ; Mouse
应用： IHC
稀释比例： IHC 1:50-200.

抗体信息

靶标： NCAPD2
别名： CAPD2, Chromosome condensation-related SMC-associated protein 1, Chromosome-associated protein D2, CND1, Condensin, hCAP-D2, hCAPD2, CND1_HUMAN
背景说明： Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. May target the condensin complex to DNA via its C-terminal domain. May promote the resolution of double-strand DNA catenanes (intertwines) between sister chromatids. Condensin-mediated compaction likely increases tension in catenated sister chromatids, providing directionality for type II topoisomerase-mediated strand exchanges toward chromatid decatenation. Required for decatenation of non-centromeric ultrafine DNA bridges during anaphase. Early in neurogenesis, may play an essential role to ensure accurate mitotic chromosome condensation in neuron stem cells, ultimately affecting neuron pool and cortex size.
Swiss Prot： Q15021
Gene ID： 9918
亚细胞定位： Cytoplasm Nucleus
免疫原： Recombinant protein of human NCAPD2
Public Immunogen Range： 1-350aa
理论分子量： 157kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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