Anti-CD46 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-CD46 Polyclonal Antibody
中文名称： 膜辅蛋白抗体
规格： 50ul ; 100ul ; 20ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应： Human预测
交叉反应： Monkey(86.7%);Chimpanzee(93.3%)
应用： IHC-P
稀释比例： IHC-P 1:100-300.

抗体信息

靶标： CD46
别名： AHUS2; Antigen defined by monoclonal antibody TRA 2 10; Antigen identified by monoclonal antibody TRA 2 10; CD46; CD46 antigen; CD46 antigen complement regulatory protein; CD46 molecule; CD46 molecule complement regulatory protein; Complement membrane cofactor protein; MCP; MCP_HUMAN; Measles virus receptor; membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen); Membrane cofactor protein; MGC26544; MIC10; TLX; TRA2.10; Trophoblast leucocyte common antigen; Trophoblast leukocyte common antigen; Trophoblast lymphocyte cross reactive antigen;
背景说明： The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.
Swiss Prot： P15529
Gene ID： 4179
亚细胞定位： Cell membrane
研究领域： 免疫学 ; 表观遗传
免疫原： A synthetic peptide of human CD46 种属同源性预测Public Immunogen Range 35-85/392aa
理论分子量： 37/39/40/41/42/43/44kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.
运输条件： 冷冻运输 种属同源性预测

产品介绍 Product Introduction

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