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- Anti-POLR3K Polyclonal Antibody,BR
Anti-POLR3K Polyclonal Antibody,BR
Anti-POLR3K Polyclonal Antibody
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产品属性 Product Attributes
基本信息
英文名称: Anti-POLR3K Polyclonal Antibody中文名称: 聚合酶III多肽K抗体
规格: 50ul ; 100ul
宿主: Rabbit
克隆类型: Polyclonal Antibody
亚型: IgG
交叉反应:: Human ; Rat ; Mouse
应用: IHC
稀释比例: IHC 1:50-200.
抗体信息
靶标: POLR3K别名: POLR3K,RPC11,My010,DNA-directed RNA polymerase III subunit RPC10,RNA polymerase III subunit C10,DNA-directed RNA polymerase III subunit K,RNA polymerase III 12.5 kDa subunit,RPC12.5,RNA polymerase III subunit C11,HsC11p,RPC11,hRPC11,My010
背景说明: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway.
Swiss Prot: Q9Y2Y1
Gene ID: 51728
亚细胞定位: Cytoplasm Nucleus
免疫原: Recombinant protein of human POLR3K
Public Immunogen Range: 1-109aa
理论分子量: 12kDa
其它标识
纯化方法: Affinity purification储存液: PBS with 50% Glycerol,0.03% Proclin300,0.5% BSA,pH 7.3.
储存条件: Store at -20℃. Avoid freeze/thaw cycles.
产品介绍 Product Introduction
使用前请离心。如有问题请及时联系我们。Quick spin before use. If you have any questions, please contact us.
注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。