Anti-PAM Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-PAM Polyclonal Antibody
中文名称： 肽酰甘氨酸α酰胺化单加氧酶抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Rat ; Mouse
应用： IHC
稀释比例： IHC 1:100-300.

抗体信息

靶标： PAM
别名： AMD_HUMAN, PAL, PAM, Pancreatic peptidylglycine alpha amidating monooxygenase, Peptidyl alpha amidating enzyme, Peptidyl alpha hydroxyglycine alpha amidating lyase, Peptidyl-alpha-hydroxyglycine alpha-amidating lyase, Peptidylamidoglycolate lyase, Peptidylglycine 2 hydroxylase, Peptidylglycine alpha amidating monooxygenase, Peptidylglycine alpha hydroxylating monooxygenase, PHM
背景说明： Bifunctional enzyme that catalyzes the post-translational modification of inactive peptidylglycine precursors to the corresponding bioactive alpha-amidated peptides, a terminal modification in biosynthesis of many neural and endocrine peptides. Alpha-amidation involves two sequential reactions, both of which are catalyzed by separate catalytic domains of the enzyme. The first step, catalyzed by peptidyl alpha-hydroxylating monoxygenase (PHM) domain, is the copper-, ascorbate-, and O2- dependent stereospecific hydroxylation (with S stereochemistry) at the alpha-carbon (C-alpha) of the C-terminal glycine of the peptidylglycine substrate. The second step, catalyzed by the peptidylglycine amidoglycolate lyase (PAL) domain, is the zinc-dependent cleavage of the N-C-alpha bond, producing the alpha-amidated peptide and glyoxylate. Similarly, catalyzes the two-step conversion of an N-fatty acylglycine to a primary fatty acid amide and glyoxylate.
Swiss Prot： P19021
Gene ID： 5066
亚细胞定位： Cell membrane Secreted
免疫原： Recombinant protein of human PAM
Public Immunogen Range： 1-350aa
理论分子量： 96/100/108kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
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注意事项 Considerations

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2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。