Anti-IL33 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-IL33 Polyclonal Antibody
中文名称： 白细胞介素33抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human
应用： IHC
稀释比例： IHC 1:50-200.

抗体信息

靶标： IL33
别名： IL33,C9orf26,DVS27,IL1F11,NF-HEV,NFEHEV,IL-33,IL 33
背景说明： Cytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells. Involved in the maturation of Th2 cells inducing the secretion of T-helper type 2-associated cytokines. Also involved in activation of mast cells, basophils, eosinophils and natural killer cells. Acts as a chemoattractant for Th2 cells, and may function as an 'alarmin', that amplifies immune responses during tissue injury.In quiescent endothelia the uncleaved form is constitutively and abundantly expressed, and acts as a chromatin-associated nuclear factor with transcriptional repressor properties, it may sequester nuclear NF-kappaB/RELA, lowering expression of its targets. This form is rapidely lost upon angiogenic or proinflammatory activation.
Swiss Prot： O95760
Gene ID： 90865
亚细胞定位： Nucleus Cytoplasm
免疫原： Recombinant protein of human IL33
Public Immunogen Range： 1-270aa
理论分子量： 26/31kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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