- 首页
- Anti-DTNBP1 Polyclonal Antibody,BR
Anti-DTNBP1 Polyclonal Antibody,BR
Anti-DTNBP1 Polyclonal Antibody
(订货以英文名为准)猜你喜欢
CAS No:9004-74-4
CAS No:13292-87-0
CAS No:25322-68-3
CAS No:115383-22-7
CAS No:27804-64-4
CAS No:76843-23-7
CAS No:102195-80-2
产品属性 Product Attributes
基本信息
英文名称: Anti-DTNBP1 Polyclonal Antibody中文名称: 肌萎缩dystrobrevin结合蛋白1抗体
规格: 50ul ; 100ul
宿主: Rabbit
克隆类型: Polyclonal Antibody
亚型: IgG
交叉反应:: Human ; Rat ; Mouse
应用: WB ; IHC
稀释比例: WB 1:1000-3000. IHC 1:50-200.
抗体信息
靶标: DTNBP1别名: Dysbindin-1, 5430437B18Rik, AW048963, dysbindin, sdy, DTNBP1, Dystrobrevin binding protein 1, Hermansky Pudlak syndrome 7 protein, HPS7, DTBP1_HUMAN, Dystrobrevin-binding protein-1, Hermansky-Pudlak syndrome 7 protein, HPS7 protein
背景说明: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Associates with the BLOC-2 complex to facilitate the transport of TYRP1 independent of AP-3 function. Plays a role in synaptic vesicle trafficking and in neurotransmitter release. Plays a role in the regulation of cell surface exposure of DRD2. May play a role in actin cytoskeleton reorganization and neurite outgrowth. May modulate MAPK8 phosphorylation. Appears to promote neuronal transmission and viability through regulating the expression of SNAP25 and SYN1, modulating PI3-kinase-Akt signaling and influencing glutamatergic release. Regulates the expression of SYN1 through binding to its promoter. Modulates prefrontal cortical activity via the dopamine/D2 pathway.
Swiss Prot: Q96EV8
Gene ID: 84062
亚细胞定位: Cytoplasm Nucleus
免疫原: Recombinant protein of human DTNBP1
Public Immunogen Range: 1-350aa
理论分子量: 30/35/39kDa
其它标识
纯化方法: Affinity purification储存液: PBS with 50% Glycerol,0.03% Proclin300,0.5% BSA,pH 7.3.
储存条件: Store at -20℃. Avoid freeze/thaw cycles.
产品介绍 Product Introduction
使用前请离心。如有问题请及时联系我们。Quick spin before use. If you have any questions, please contact us.
注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。