Anti-PAK5 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-PAK5 Polyclonal Antibody
中文名称： p21蛋白相关激活激酶7抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Rat ; Mouse
应用： IHC
稀释比例： IHC 1:100-300.

抗体信息

靶标： PAK5
别名： Serine/threonine-protein kinase PAK 5;p21-activated kinase 5;PAK-5;p21-activated kinase 7;PAK-7;KIAA1264;PAK7;
背景说明： Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, proliferation or cell survival. Activation by various effectors including growth factor receptors or active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Phosphorylates the proto-oncogene RAF1 and stimulates its kinase activity. Promotes cell survival by phosphorylating the BCL2 antagonist of cell death BAD. Phosphorylates CTNND1, probably to regulate cytoskeletal organization and cell morphology. Keeps microtubules stable through MARK2 inhibition and destabilizes the F-actin network leading to the disappearance of stress fibers and focal adhesions.
Swiss Prot： Q9P286
Gene ID： 57144
亚细胞定位： Cytoplasm Nucleus
免疫原： Recombinant protein of human PAK5
Public Immunogen Range： 1-350aa
理论分子量： 81kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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