Anti-BLOC1S2 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-BLOC1S2 Polyclonal Antibody
中文名称： 溶酶体细胞器的生物发生复合物1,亚基2抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Rat ; Mouse
应用： IHC
稀释比例： IHC 1:50-200.

抗体信息

靶标： BLOC1S2
别名： BLOS2;BORCS2;CEAP;CEAP11
背景说明： Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes (PubMed:15102850, PubMed:17182842). In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension (By similarity). As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor (PubMed:25898167). May play a role in cell proliferation (PubMed:15381421).
Swiss Prot： Q6QNY1
Gene ID： 282991
亚细胞定位： Cytoplasm
免疫原： Recombinant protein of human BLOC1S2
Public Immunogen Range： 1-99aa
理论分子量： 11/16kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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