Anti-CHMP5 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-CHMP5 Polyclonal Antibody
中文名称： 带电多囊体蛋白5抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Rat ; Mouse
应用： IHC
稀释比例： IHC 1:50-200.

抗体信息

靶标： CHMP5
别名： apoptosis-related protein PNAS-2 ,C9orf83 ,CGI 34 ,Charged multivesicular body protein 5 ,CHMP 5 ,CHMP family, member 5 ,chmp5 ,CHMP5_HUMAN ,Chromatin modifying protein 5 ,Chromatin-modifying protein 5 ,Chromosome 9 open reading frame 83 ,HGNC:26942 ,HSPC177 ,hVps60 ,PNAS 2 ,SNF7 domain containing protein 2 ,SNF7 domain-containing protein 2 ,SNF7DC2 ,Vacuolar protein sorting 60 ,Vacuolar protein sorting-associated protein 60 ,Vps60
背景说明： Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. Involved in HIV-1 p6- and p9-dependent virus release.
Swiss Prot： Q9NZZ3
Gene ID： 51510
亚细胞定位： Cytoplasm
免疫原： Recombinant protein of human CHMP5
Public Immunogen Range： 1-219aa
理论分子量： 20/25kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
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注意事项 Considerations

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