Anti-IKZF4 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-IKZF4 Polyclonal Antibody
中文名称： EOS蛋白抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Mouse
应用： IHC
稀释比例： IHC 1:50-200.

抗体信息

靶标： IKZF4
别名： EOS, Eos protein, IKAROS family zinc finger 4 (Eos), IKAROS family zinc finger 4, Ikaros family zinc finger protein 4, IKZF4, IKZF4_HUMAN, KIAA1782, Zinc finger protein Eos (IKAROS family zinc finger protein 4), Zinc finger protein Eos, Zinc finger protein, subfamily 1A, 4 (Eos), Zinc finger protein, subfamily 1A, member 4, Zinc finger transcription factor Eos, ZNFN1A4
背景说明： DNA-binding protein that binds to the 5'GGGAATRCC-3' Ikaros-binding sequence. Transcriptional repressor. Interacts with SPI1 and MITF to repress transcription of the CTSK and ACP5 promoters via recruitment of corepressors SIN3A and CTBP2. May be involved in the development of central and peripheral nervous systems. Essential for the inhibitory function of regulatory T-cells (Treg). Mediates FOXP3-mediated gene silencing in regulatory T-cells (Treg) via recruitment of corepressor CTBP1 (By similarity).
Swiss Prot： Q9H2S9
Gene ID： 64375
亚细胞定位： Cytoplasm
免疫原： A synthetic peptide of human IKZF4
Public Immunogen Range： 460-510/585aa
理论分子量： 60/64kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。