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Anti-GNL3L Polyclonal Antibody,BR
Anti-GNL3L Polyclonal Antibody
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产品属性 Product Attributes
基本信息
英文名称: Anti-GNL3L Polyclonal Antibody中文名称: 鸟嘌呤核苷酸结合蛋白样蛋白3样蛋白抗体
规格: 50ul ; 100ul
宿主: Rabbit
克隆类型: Polyclonal Antibody
亚型: IgG
交叉反应:: Mouse ; Human预测
交叉反应:: Cow
应用: IHC
稀释比例: IHC 1:50-200.
抗体信息
靶标: GNL3L别名: GNL3L_HUMAN, FLJ10613, Guanine nucleotide binding protein-like 3 (nucleolar)-like, novel GTPase,
背景说明: Stabilizes TERF1 telomeric association by preventing TERF1 recruitment by PML. Stabilizes TERF1 protein by preventing its ubiquitination and hence proteasomal degradation. Does so by interfering with TERF1-binding to FBXO4 E3 ubiquitin-protein ligase. Required for cell proliferation. By stabilizing TRF1 protein during mitosis, promotes metaphase-to-anaphase transition. Stabilizes MDM2 protein by preventing its ubiquitination, and hence proteasomal degradation. By acting on MDM2, may affect TP53 activity. Required for normal processing of ribosomal pre-rRNA. Binds GTP.
Swiss Prot: Q9NVN8
Gene ID: 54552
亚细胞定位: Nucleus Cytoplasm
免疫原: A synthetic peptide of human GNL3L
Public Immunogen Range: 1-51/582aa
理论分子量: 66kDa
其它标识
纯化方法: Affinity purification储存液: PBS with 50% Glycerol,0.03% Proclin300,0.5% BSA,pH 7.3.
储存条件: Store at -20℃. Avoid freeze/thaw cycles.
产品介绍 Product Introduction
使用前请离心。如有问题请及时联系我们。Quick spin before use. If you have any questions, please contact us.
注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。
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