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Anti-PARP Monoclonal Antibody,BR
Anti-PARP Monoclonal Antibody
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产品属性 Product Attributes
基本信息
英文名称: Anti-PARP Monoclonal Antibody中文名称: 多腺苷二磷酸多聚酶抗体
规格: 100ul ; 50ul
宿主: Mouse
亚型: IgG1
克隆号: M3
交叉反应: Mouse ; Human
应用: WB ; IHC-P
稀释比例: WB 1:2000-4000. IHC-P 1:50-200.
抗体信息
靶标: PARP别名: ADPRT;ADPRT 1;ADPRT1;ARTD1;PARP;PARP-1;PPOL;pADPRT-1;poly(ADP-ribose) polymerase 1
背景说明: Poly [ADP-ribose] polymerase 1 (PARP-1) also known as NAD+ ADP-ribosyltransferase 1 or poly[ADP-ribose] synthase 1 is an enzyme that in humans is encoded by the PARP1 gene. PARP1 has a role in repair of single-stranded DNA (ssDNA) breaks. Knocking down intracellular PARP1 levels with siRNA or inhibiting PARP1 activity with small molecules reduces repair of ssDNA breaks. In the absence of PARP1, when these breaks are encountered during DNA replication, the replication fork stalls, and double-strand DNA (dsDNA) breaks accumulate.
Swiss Prot: P09874
Gene ID: 142
亚细胞定位: Nucleus nucleolus
研究领域: 免疫学 ; 表观遗传
免疫原: A synthetic peptide coupled to KLH
理论分子量: 116kDa
其它标识
纯化方法: Affinity purification储存液: PBS with 50% Glycerol,0.03% Proclin300,0.5% BSA,pH 7.3.
储存条件: Store at -20℃. Avoid freeze/thaw cycles.
运输条件: 冷冻运输
产品介绍 Product Introduction
暂无数据注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。
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