Anti-GAPDH Monoclonal antibody,BR

英文名称:Anti-GAPDH Monoclonal antibody
宿主:Mouse
别名:GAPDH
交叉反应:Human Rat Mouse Monkey Dog Chicken Hamster Rabbit Sheep Pig Insect Yeast
应用:WB IHC IF
稀释比例:WB 1:3000-8000. IHC 1:100-300. IF 1:100-200.
蛋白分子量:36kDa
Gene ID:2597
保存:Store at -20°C. Avoid freeze / thaw cycles.
储存液:Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法:Affinity purification
亚型:IgG1
免疫原:Recombinant protein of human GAPDH
性状:液体
亚细胞定位:Cytoskeleton Cytosol Nucleus
Swiss Prot:P04406
背景资料:Glyceraldehyde 3 phosphate dehydrogenase (GAPDH) is well known as one of the key enzymes involved in glycolysis. As well as functioning as a glycolytic enzyme in cytoplasm, recent evidence suggests that mammalian GAPDH is also involved in a great number of intracellular proceses such as membrane fusion, microtubule bundling, phosphotransferase activity, nuclear RNA export, DNA replication, and DNA repair. During the last decade a lot of data appeared concerning the role of GAPDH in different pathologies including prostate cancer progression, programmed neuronal cell death, age related neuronal diseases, such as Alzheimer's and Huntington's disease. GAPDH is expressed in all cells. It is constitutively expressed in almost all tissues at high levels. There are however some physiological factors such as hypoxia and diabetes that increase GAPDH expression in certain cell types. GAPDH molecule is composed of four 36kDa subunits.
Public Immunogen Range:Recombinant protein of human GAPDH
克隆类型:Monoclonal Antibody
规格:50ul, 100ul, 注意：
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