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- Recombinant Human GITR/TNFRSF18/CD357,BR
Recombinant Human GITR/TNFRSF18/CD357,BR
Recombinant Human GITR/TNFRSF18/CD357
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产品属性 Product Attributes
基本信息
别名: Tumor necrosis factor receptor superfamily member 18;TNFRSF18;Glucocorticoid-induced TNFR-related protein;CD357;TNFRSF18;AITR;GITR中文名称: Recombinant Human GITR/TNFRSF18/CD357
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状): Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
产品信息
背景说明: Tumor necrosis factor receptor superfamily member 18(Gitr) contains 3 TNFR-Cys repeats and it have four isforms.IsformA、isformB and isformC is single-pass type I membrane protein and isformD is asecreted protein.The protein is the receptor for TNFSF18.It seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death.It mediated NF-kappa-B activation via the TRAF2/NIK pathway.It binds to TRAF1,TRAF2,and TRAF3,but not TRAF5 and TRAF6 and binds through its C-terminus to SIVA1/SIVA.It preferentially expressed in activated T lymphocytes and up-regulated in peripherical mononuclear cells after antigen stimulation/lymphocyte activation.来源: Human Cells
其它标识
溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.
产品介绍 Product Introduction
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1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。