Recombinant Mouse CTLA-4/CD152/Cytotoxic T-lymphocyte Protein 4,BR

产品属性 Product Attributes

基本信息

别名： Cytotoxic T-lymphocyte protein 4;Cytotoxic T-lymphocyte-associated antigen 4;CTLA-4;CD152;Ctla4
中文名称: Recombinant Mouse CTLA-4/CD152/Cytotoxic T-lymphocyte Protein 4
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Mouse Cytotoxic Tlymphocyte 4(CTLA-4，CD152)，is a type I transmembrane T cell inhibitory molecule.Within the ECD，Mouse CTLA-4 shares 68% aa sequence identity with human.CTLA4 is similar to the T cell costimulatory protein CD28 since both of the molecules bind to CD80 and CD86 on antigen-presenting cells.CTLA4 transmits an inhibitory signal to T cells，whereas CD28 transmits a stimulatory signal.Intracellular CTLA4 is also found inregulatory T cells and may play an important role in their functions.T cell activation through the T cell receptor and CD28 leads to increased expression of CTLA4.Genetic variations of CTLA4 have been associated with susceptibility to systemic lupus erythematosus(SLE)，Gravesdisease(GRD)，Celiac disease type3(CELIAC3) and Hepatitis B virus infection(HBVinfection).
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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