Recombinant Human ALCAM/CD166,BR

产品属性 Product Attributes

基本信息

别名： CD166 antigen;Activated leukocyte cell adhesion molecule;CD166;ALCAM;MEMD
中文名称: Recombinant Human ALCAM/CD166
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Activated leukocyte cell adhesion molecule (ALCAM)，also named as CD166 and MEMD，is a typeI transmembrane glycoprotein of immunoglobulin superfamily，which mediates homotypic and heterotypic interactions between cells.ALCAM is expressed on thymic epithelium，microvascular endothelium，activated lymphocytes and monocytes，and monocytederived dendritic cells.ALCAM mediates low-affinity adhesion with itself or the cysteine-rich scavenger receptor CD6 to regulate T cell development，immunological synapses(IS)，and cell migration through endothelial junctions.ALCAM on thymic epithelia mediates adhesion to CD6 on CD4+CD8+ T cells.Adhesion of ALCAM expressing antigen presenting cells and CD6-expressing T cells stabilizes the early IS，while later it enhances CD3 effects on T cell proliferation，CD25 expression，and Th1 commitment.ALCAM may influence expression or adhesion of the neuronal adhesion molecule NCAML1，both in the developing retina and invasive melanoma.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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