Recombinant Human GFR alpha-1/GFRA1/GDNF family receptor alpha-1/RETL1/RET ligand 1/TRNR1,BR

产品属性 Product Attributes

基本信息

别名： GFRα1;GDNF Family Receptor Alpha-1;GDNF Receptor Alpha-1;GDNFR-Alpha-1;GFR-Alpha-1;RET Ligand 1;TGF-Beta-Related Neurotrophic Factor Receptor 1;GFRA1;GDNFRA;RETL1;TRNR1
中文名称: Recombinant Human GFR alpha-1/GFRA1/GDNF family receptor alpha-1/RETL1/RET ligand 1/TRNR1
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Glial Cell Line-Derived Neurotrophic Factor Family Receptor α-1 (GDNFRα1) is a glycosylphosphatidylinositol (GPI) linked cell surface protein belonging to GDNF-family receptor α subtype which consists of at least four members.GFRα1and GFRα2 are the cognate co-receptor for the neurotrophic factor neurturin mediating the NRTN-induced autophosphorylation and activation of the RET tyrosine kinase receptor.Soluble GFRαs released enzymatically from the cell surface by phosphatidylinositol phospholipase C，as well as recombinantly produced soluble GFRα1，can also bind with high affinity to GDNF and trigger the activation of Ret tyrosine kinase.Human GFRα1 shares 93% amino acid identity with mouse GFRα1.The expression of the various GFRαs are differentially regulated in the central and peripheral nervous system，suggesting complementary roles for the GFRαs in mediating the activities of the GDNF family of neurotrophic factors.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

暂无数据

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。