Recombinant Human HB-EGF/proHB-EGF/Heparin Binding EGF like Growth Factor,BR

产品属性 Product Attributes

基本信息

别名： Diphtheria toxin receptor;DTR;HEGFL;heparin-binding EGF-like growth factor;DTS;DTSF;heparin-binding epidermal growth factor;proheparin-binding EGF-like growth factor;HB-EGF;pro HB-EGF
中文名称: Recombinant Human HB-EGF/proHB-EGF/Heparin Binding EGF like Growth Factor
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Heparin-binding EGF-like growth factor (HB-EGF) is a 12-16 kDa member of the epidermal growth factor (EGF) family.It possesses an EGF-like domain，and a heparin-binding motif.Mature HB-EGF is a soluble peptide that arises from proteolytic processing of the transmembrane form.Human HB-EGF shows 76% and 73% aa sequence identity with rat and mouse HB-EGF，respectively.It is required for normal cardiac valve formation and normal heart function，promotes smooth muscle cell proliferation.It may be involved in macrophage-mediated cellular proliferation; it is mitogenic for fibroblasts，but not endothelial cells.HB-EGF classified as a group 2 ErbB ligand based on its ability to activate both the EGF/ErbB1 and ErbB4 receptors.Activity associated with ErbB4 binding appears to be limited to non-mitogenic actions，while EGFR binding induces both mitogenic and non-mitogenic activity.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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