Recombinant Human M-CSF R/CSF1R/CD115/Macrophage Colony-stimulating Factor 1 Receptor,BR

产品属性 Product Attributes

基本信息

别名： Macrophage colony-stimulating factor 1 receptor;CSF-1 receptor;CSF-1-R;CSF-1R;M-CSF-R;Proto-oncogene c-Fms;CD115;CSF1R;FMS
中文名称: Recombinant Human M-CSF R/CSF1R/CD115/Macrophage Colony-stimulating Factor 1 Receptor
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Macrophage colony-stimulating factor 1 receptor (CSF1R) is a member of the type III subfamily of receptor tyrosine kinases that also includes receptors for SCF and PDGF.These receptors each contain five immunoglobulin-like domains in their extracellular domain (ECD) and a split kinase domain in their intracellular region.CSF1R is expressed primarily on cells of the monocyte/macrophage lineage，dendritic cells，stem cells and in the developing placenta.CSF1 and its receptor (CSF1R，product of c-fms proto-oncogene) were initially implicated as essential for normal monocyte development as well as for trophoblastic implantation.It plays an important role in the regulation of osteoclast proliferation and differentiation，the regulation of bone resorption，and is required for normal bone and tooth development.It is required for normal male and female fertility，and for normal development of milk ducts and acinar structures in the mammary gland during pregnancy.Aberrant expression of CSF1 or CSF1R may play a role in inflammatory diseases，such as rheumatoid arthritis，glomerulonephritis，atherosclerosis，and allograft rejection.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

暂无数据

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。