Recombinant Mouse Interleukin-21 Receptor/IL-21R,BR

产品属性 Product Attributes

基本信息

别名： Interleukin-21 receptor;IL-21 receptor;IL-21R;Il21r;Nilr
中文名称: Recombinant Mouse Interleukin-21 Receptor/IL-21R
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Interleukin-21 receptor (IL-21R) is a type I transmembrane glycoprotein within the class I cytokine receptor family，type 4 subfamily.IL-21R is expressed mainly on B cells，NK cells，and activated T cells，but is also found on dendritic cells，alternatively activated macrophages，intestinal lamina propria fibroblasts and epithelial cells，and keratinocytes.Both IL-21 and IL-4 are necessary for efficient B cell IgG1 production and normal germinal center architecture.B cell IL-21 R engagement induces Blimp-1(which mediates plasma cell differentiation)，and is important for memory responses.IL-21R engagement on mouse NK cells enhances their cytotoxic activity and IFN-γ production.IL-21R engagement on CD8+ T cells aids control of viral infection and tumor growth IL-21R is also necessary for sufficient numbers of regulatory T cells to combat chronic inflammation.IL-21R expression is often up-regulated in allergic skin inflammation，systemic lupus erythematosus and diffuse large B cell lymphoma (DLBCL).
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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