Recombinant Mouse P-selectin/CD62P,BR

产品属性 Product Attributes

基本信息

别名： P-selectin;CD62 antigen-like family member P;Granule membrane protein 140;GMP-140;Leukocyte-endothelial cell adhesion molecule 3;LECAM3;PADGEM
中文名称: Recombinant Mouse P-selectin/CD62P
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： P-selectin/CD62P is a single-pass type I membrane protein which is a member of the Selectin family.It consists 768 amino acid (aa).P-selectin is a cell surface glycoprotein expressed by activated platelets and endothelial cells.It induced expression in lung，liver，kidney and heart after endotoxin treatment.Ca2+-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes.It mediates the interaction of activated endothelial cells or platelets with leukocytes.The ligand recognized is sialyl-Lewis X.it also mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with PSGL1.P-selectin interacts with SNX17，PSGL1/SEPL，PODXL2，mediates neutrophil adhesion and leukocyte rolling.This interaction requires the sialyl-Lewis X epitope of PSGL1 and PODXL2，and specific tyrosine sulfation on PSGL1.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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