Recombinant Human ROR1/Inactive tyrosine-protein kinase transmembrane receptor ROR1/Neurotrophic tyrosine kinase,BR

产品属性 Product Attributes

基本信息

别名： neurotrophic tyrosine kinase receptor-related 1;receptor tyrosine kinase-like orphan receptor 1;ROR1;tyrosine-protein kinase transmembrane receptor ROR1
中文名称: Recombinant Human ROR1/Inactive tyrosine-protein kinase transmembrane receptor ROR1/Neurotrophic tyrosine kinase
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： ROR1，also known as Neurotrophic tyrosine kinase，receptor-related 1，belongs to the ROR subfamily ofTyr protein kinase family，a protein kinase superfamily.It has very low kinase activity in vitro and is unlikelyto function as a tyrosine kinase in vivo.Human ROR1 is a type I transmembrane protein with 937 aminoacids (aa) in length.It contains a 29 aa signal sequence，a 377 aa extracellular domain (ECD)，a 21 aatransmembrane segment，and a 510 aa cytoplasmic region.Human ROR1 shares 97% and 58% aa sequenceidentity with mouse ROR1 and human ROR2，respectively.ROR1 may act as a receptor for wnt ligandWNT5A which may result in the inhibition of WNT3A-mediated signaling.ROR1 expressed strongly inhuman heart，lung and kidney，but weakly in the CNS.Its Isoform Short is strongly expressed in fetal andadult CNS and in a variety of human cancers，including those originating from CNS or PNS neuroectoderm.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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