Recombinant Human ACVR2B/Activin receptor type-2B,BR

产品属性 Product Attributes

基本信息

别名： Activin Receptor Type-2B;Activin Receptor Type IIB;ACTR-IIB;ACVR2B
中文名称: Recombinant Human ACVR2B/Activin receptor type-2B
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Activin proteins that belong to the transforming growth factor-beta (TGF-β) superfamily，exert their biological actions by binding to heteromeric receptor complexes of type I and type II serine/threonine kinase receptors.On ligand binding，type I and II receptors form a stable complex，resulting in phosphorylation of type I receptors by type II receptors with constitutive kinase activity，and subsequently initiates the activation of downstream molecules including the endogenous Smads.ActRIIB，also known as ActRIIB，is a type II receptor containing an extracellular domain (ECD)，a transmembrane segment，and a cytoplasmic region that includes the kinase domain.ActRIIB is a receptor for activin A，activin B and inhibin A.Multiple ActRIIB isoforms can also be generated，which bind activin isoforms with different affinities.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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