Recombinant Human PDGF R beta/PDGFRB/PDGFRβ/CD140b,BR

产品属性 Product Attributes

基本信息

别名： Platelet-Derived Growth Factor Receptor Beta;PDGF-R-Beta;PDGFR-Beta;Beta Platelet-Derived Growth Factor Receptor;Beta-Type Platelet-Derived Growth Factor Receptor;CD140 Antigen-Like Family Member B;Platelet-Derived Growth Factor Receptor 1;PDGFR-1;CD140b;PDGFRB;PDGFR;PDGFR1
中文名称: Recombinant Human PDGF R beta/PDGFRB/PDGFRβ/CD140b
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Platelet-Derived Growth Factor Receptor β (PDGFR-β) is a member of the protein kinase superfamily and CSF-1/PDGF receptor subfamily.The PDGF family consists of PDGF-A，-B，-C and -D，which form either homo- or heterodimers (PDGF-AA，-AB，-BB，-CC，-DD).The four PDGFs are inactive in their monomeric forms.The PDGFs bind to the protein tyrosine kinase receptors PDGF receptor-α and -β.These two receptor isoforms dimerize upon binding the PDGF dimer，leading to three possible receptor combinations，namely -αα，-ββ and -αβ.The extracellular region of the PDGF receptor-β consists of five immunoglobulin-like domains while the intracellular part is a tyrosine kinase domain.In addition to being a potent mitogen for cells of mesenchymal origin，PDGF has also been shown to be a potent chemoattractant for mesenchymal cells，mononuclear cells，and neutrophils and has been reported to be important in the modification of cellular matrix constituents.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/μg(1 EU/μg)as determined by LAL test.

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注意事项 Considerations

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