Recombinant Human Activin RIIA/Activin receptor type IIA/ACVR2A,BR

产品属性 Product Attributes

基本信息

别名： Activin Receptor Type-2A;Activin Receptor Type IIA;ACTR-IIA;ACTRIIA;ACVR2A;ACVR2
中文名称: Recombinant Human Activin RIIA/Activin receptor type IIA/ACVR2A
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Activin Receptor Type-2A is a protein that in humans is encoded by the ACVR2A gene.ACVR2A is an activin type 2 receptor.This gene encodes activin A type II receptor.Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins.Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors.These receptors are all transmembrane proteins，composed of a ligand-binding extracellular domain with cysteine-rich region，a transmembrane domain，and a cytoplasmic domain with predicted serine/threonine specificity.Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors.Type I and II receptors form a stable complex after ligand binding，resulting in phosphorylation of type I receptors by type II receptors.Type II receptors are considered to be constitutively active kinases.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/μg(1 EU/μg)as determined by LAL test.

产品介绍 Product Introduction

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注意事项 Considerations

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3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。