Recombinant Human DR6/TNFRSF21,BR

产品属性 Product Attributes

基本信息

别名： Tumor Necrosis Factor Receptor Superfamily Member 21;Death Receptor 6;CD358;TNFRSF21;DR6;UNQ437/PRO868
中文名称: Recombinant Human DR6/TNFRSF21
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
纯度: ≥85% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Tumor Necrosis Factor Receptor Superfamily Member 21 (TNFRSF21) is a type I transmembrane receptor that includes four extracellular cysteine-rich motifs and a cytoplasmic death domain.DR6 is highly expressed in heart，brain，placenta，pancreas，lymph node，thymus and prostate.DR6 may activate NF-kappa-B and JNK to promote apoptosis and T-cell differentiation.In addition，DR6 binds with N-APP，which is released by the deprivation of Trophic-factor.It triggers caspase activation and degeneration of both neuronal cell bodies (via caspase-3) and axons (via caspase-6).DR6 is also expressed on the tumor cell lines and can be induced by TNF-α.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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