Recombinant Human FAM3B/C21orf11/ORF9,BR

产品属性 Product Attributes

基本信息

别名： Sialic acid-binding Ig-like lectin 9;Siglec-9;CDw329;Protein FOAP-9;SIGLEC9
中文名称: Recombinant Human FAM3B/C21orf11/ORF9
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： FAM3B，also known as Pancreatic-derived factor (PANDER)，is an islet-specific secreted cytokine specifically expressed at high levels in the islets of Langerhans of the endocrine pancreas.FAM3B can induce apoptosis of alpha and beta cells in a dose- and time-dependent manner.Previous studies showed that FAM3B regulates glucose and lipid metabolism through interaction with liver and endocrine pancreas.FAM3B silencing activates both extrinsic and intrinsic apoptotic pathways.In general，silencing FAM3B promoted p53 phosphorylation and induced p53 accumulation by decreasing Mdm2 expression，which resulted in apoptotic cell death.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
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3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。