Recombinant Cynomolgus SIRPA/CD172a/Signal-Regulatory Protein alpha-1,BR

产品属性 Product Attributes

基本信息

别名： Tyrosine-Protein Phosphatase Non-Receptor Type Substrate 1;SHP Substrate 1;SHPS-1;Brain Ig-Like Molecule with Tyrosine-Based Activation Motifs;Bit;CD172 Antigen-Like Family Member A;Inhibitory Feceptor SHPS-1;Macrophage Fusion Receptor;MyD-1 Antigen;Signal-Regulatory Protein Alpha-1;Sirp-Alpha-1;Signal-Regulatory Protein Alpha-2;Sirp-Alpha-2;Signal-Regulatory Protein Alpha-3;Sirp-Alpha-3;p84;CD172a;SIRPA;BIT;MFR;MYD1;PTPNS1;SHPS1;SIRP
中文名称: Recombinant Cynomolgus SIRPA/CD172a/Signal-Regulatory Protein alpha-1
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Signal Regulatory Protein α (SIRP α ) is a monomeric approximately 90 kD type I transmembrane glycoprotein.The 504 amino acid human SIRPα contains two Ig-like C1-type domains and one Ig-like V-type domain.SIRPα can express in various tissues，mainly on brain and myeloid cells，including macrophages，neutrophils，dendritic and Langerhans cells.It also can detect in neurons，smooth muscle and endothelial cells.SIRPA is an immunoglobulin-like cell surface receptor for CD47.SIRPα acts as docking protein and induces translocation of PTPN6，PTPN11 and other binding partners from the cytosol to the plasma membrane.SIRPα shows adhesion of cerebellar neurons，neurite outgrowth and glial cell attachment.SIRP α engagement generally produces a negative regulatory signal; it may mediate negative regulation of phagocytosis，mast cell activation and dendritic cell activation.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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