Recombinant Human Ubiquitin carboxyl-terminal hydrolase 14/USP14,BR

产品属性 Product Attributes

基本信息

别名： Ubiquitin Carboxyl-Terminal Hydrolase 14;Deubiquitinating Enzyme 14;Ubiquitin Thioesterase 14;Ubiquitin-Specific-Processing Protease 14;USP14;TGT
中文名称: Recombinant Human Ubiquitin carboxyl-terminal hydrolase 14/USP14
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, 20% Glycerol, pH 8.0.
纯度: ≥90% as determined by reducing SDS-PAGE.
储存条件: Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

产品信息

背景说明： Ubiquitin Carboxyl-Terminal Hydrolase 14 (USP14) belongs to the ubiquitin-specific processing (USP) family which is a deubiquitinating enzyme (DUB) with His and Cys domains.USP14 located in the cytoplasm is a proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins.USP14 acts also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1.In addition，USP14 is indispensable for synaptic development and function at neuromuscular junctions，required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis.
来源： E.coli

其它标识

内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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