Recombinant Human Tyrosine-protein Kinase Receptor TYRO3/DTK,BR

产品属性 Product Attributes

基本信息

别名： Tyrosine-protein kinase receptor TYRO3;Tyrosine-protein kinase BYK;Tyrosine-protein kinase DTK;Tyrosine-protein kinase RSE;Tyrosine-protein kinase SKY;Tyrosine-protein kinase TIF;TYRO3;BYK;DTK;RSE;SKY;TIF
中文名称: Recombinant Human Tyrosine-protein Kinase Receptor TYRO3/DTK
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Axl (Ufo，Ark)，Dtk (Sky，Tyro3，Rse，Brt) and Mer (human and mouse homologues of chicken cEyk)constitute a new receptor tyrosine kinase subfamily.The extracellular domain of these proteins contain two Ig-like motifs and two fibronectin type III motifs.This characteristic topology is also found in neural cell adhesion molecules and in receptor tyrosine phosphatases.All three receptors bind the vitamin K-dependent protein growth-arrest specific gene 6 (Gas6) which is structurally related to the anticoagulation factor protein S.The binding affinities for Gas6 is in the order of Axl > Dtk > Mer.Gas6 binding induces tyrosine phosphorylation and downstream signaling pathways that can lead to cell proliferation，migration，or the prevention of apoptosis.Dtk is widely expressed during embryonic development.In adults，Dtk is predominantly expressed in neurons in restricted regions of the brain.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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