Recombinant Mouse MAG/Siglec-4a,BR

产品属性 Product Attributes

基本信息

别名： Myelin-Associated Glycoprotein;MAG;Siglec-4a
中文名称: Recombinant Mouse MAG/Siglec-4a
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Myelin-Associated Glycoprotein (MAG，Siglec-4a)，is a type I transmembrane glycoprotein belonging to the Siglec family.It is composed of an extracellular segment containing five Ig-like domains，a single transmembrane segment，and a cytoplasmic domain.Mouse MAG shares 95% and 99% aa sequence identity with human and rat MAG，respectively.MAG functions as an adhesion molecule during neural development.It preferentially binds to alpha -2，3-linked sialic acid terminal structures found on cell surface molecules.MAG is selectively expressed by myelinating oligodendrocytes and Schwann cells and plays an important role in axon-myelin stability.MAG is also reported to regulate the axon cytoskeleton and support the distribution of axon molecules at the nodes of Ranvier.In addition，it has been identified as a major inhibitor of neurite outgrowth.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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