Recombinant Human BTLA/B-and-T-lymphocyte attenuator/CD272,BR

产品属性 Product Attributes

基本信息

别名： B- and T-Lymphocyte Attenuator;B- and T-Lymphocyte-Associated Protein;CD272;BTLA
中文名称: Recombinant Human BTLA/B-and-T-lymphocyte attenuator/CD272
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： B- and T-Lymphocyte Attenuator (BTLA) is a single-pass type I membrane protein containing 1 Ig-like V-type (immunoglobulin-like) domain.BTLA expression is induced during activation of T cells，and BTLA remains expressed on Th1 cells but not Th2 cells.Like PD1 and CTLA4，BTLA interacts with a B7 homolog，B7H4.However，unlike PD-1 and CTLA-4，BTLA displays T-Cell inhibition via interaction with tumor necrosis family receptors (TNF-R)，not just the B7 family of cell surface receptors.BTLA is a lymphocyte inhibitory receptor that inhibits lymphocytes during immune response.BTLA also is a ligand for tumor necrosis factor (receptor) superfamily，member 14 (TNFRSF14)，also known as herpes virus entry mediator (HVEM).BTLA-HVEM complexes negatively regulate T-cell immune responses.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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