Recombinant Human Siglec-5/CD170/CD33L2/CD33 antigen-like 2/Obesity-binding protein 2/OBBP2,BR

产品属性 Product Attributes

基本信息

别名： Sialic acid-binding Ig-like lectin 5;Siglec-5;CD33 antigen-like 2;Obesity-binding protein 2;OB-BP2;CD170
中文名称: Recombinant Human Siglec-5/CD170/CD33L2/CD33 antigen-like 2/Obesity-binding protein 2/OBBP2
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Human Siglec-5 are Itype(Igtype) lectins belonging to the Ig superfamily，They are characterized by an N terminal Ig-like V type domain which mediates sialic acid binding，followed by varying numbers of Ig-like C2 type domains.SIGLEC5 has also been designated CD170，they are expressed by monocytic or myeloid lineage cells，and also found at high levels in peripheral blood leukocytes，spleen，bone marrow and at lower levels in lymph node，lung，appendix，placenta，pancreas and thymus.SIGLEC5 are expressed by monocytes and neutrophils but absent from leukemic cell lines representing early stages of myelomonocytic differentiation.Siglec5 to 11 share a high degree of sequence similarity with CD33/Siglec3 both in their extracellular and intracellular regions.They are collectively referred to as CD33 related Siglecs.One remarkable feature of the CD33 related Siglecs is their differential expression pattern within the hematopoietic system This fact，together with the presence of two conserved immunoreceptor tyrosinebased inhibition motifs (ITIMs) in their cytoplasma tails，suggests that CD33 related Siglecs are involved in the regulation of cellular activation within the immune system.
来源： Human Cells

其它标识

溶剂: Dissolve the lyophilized protein in distilled water.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

暂无数据

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。