Recombinant Mouse Ectodysplasin A2 Receptor/EDA2R/TNFRSF27,BR

产品属性 Product Attributes

基本信息

别名： Ectodysplasin A2 receptor;EDA-A2 receptor;EDA-A2R;Tumor necrosis factor receptor superfamily member XEDAR;Tumor necrosis factor receptor superfamily member 27;X-linked ectodysplasin-A2 receptor;EDAA2R;TNFRSF27;XEDAR;EDAR2
中文名称: Recombinant Mouse Ectodysplasin A2 Receptor/EDA2R/TNFRSF27
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Tumor necrosis factor receptor superfamily member 27，also known as XEDAR and EDA2R，is a type III transmembrane protein of the TNFR superfamily.EDA2R consists of extracellular domain (ECD) with 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide.EDA2R is widely expressed，notably in embryonic basal epidermal cells and maturing hair follicles.Even though it does not contain a cytoplasmic death domain，EDA2R can associate with Fas and induce EDA-A2 dependent apoptosis.Its transcription is directly induced by p53，and it mediated cell death is p53 dependent.it is down-regulated in breast，colon，and lung cancers，particularly in cases with p53 mutations.It also plays a role in EDA-A2 induced skeletal muscle degeneration and osteoblast differentiation.Mutations in the EDA gene are associated with the X-linked form of Hypohidrotic Ectodermal Dysplasia (HED)，a disease typically characterized by abnormal hair，teeth and sweat glands.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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