Recombinant Mouse Nephroblastoma Overexpressed Gene/NOV/CCN3/IGFBP-9,BR

产品属性 Product Attributes

基本信息

别名： Protein NOV homolog;NovH;CCN family member 3;Nephroblastoma-overexpressed gene protein homolog;Nov
中文名称: Recombinant Mouse Nephroblastoma Overexpressed Gene/NOV/CCN3/IGFBP-9
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： NOV，also called CCN3，is a secreted protein of CCN family members.CCN family members are highly conserved cysteine rich proteins sharing a common modular structure having 4 conserved domains，insulin-like growth factor-binding protein (IGFBP) domain，von Willebrand type C (VWC) domain，thrombospondin-1 (TSP-1) domain，and C-terminal (CT) domain (absent in CCN5).By specific interactions with these domains，CCN proteins modulate multiple signalling pathways including BMPs，Wnt，TGFs，Notch and integrins to regulate cell proliferation，differentiation，adhesion，migration，angiogenesis，and survival.CCN3 is firstly characterized as a promoter of progenitor activity of human hematopoietic stem cells，as knockdown of CCN3 can abrogate the function of primitive progenitors.Recent studies showed that CCN3 is also actively involved in the process of wound healing.CCN3 is highly expressed in granulation tissues of cutaneous wounds and capable of inducing synthetic responses of fibroblasts.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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