Recombinant Human CD24/Signal Transducer CD24,BR

产品属性 Product Attributes

基本信息

别名： Signal transducer CD24;Small cell lung carcinoma cluster 4 antigen;CD24;CD24A
中文名称: Recombinant Human CD24/Signal Transducer CD24
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Signal Transducer CD24 is a heavily and variably glycosylated GPI-linked sialoprotein.Human CD24 is expressed on B lineage cells and granulocytes，on epithelial，neuronal，and muscle cells，and on a range of tumor cells.CD24 expression is regulated during lineage development and with the activation of various cell types.Antibody crosslinking of CD24 enhances the induction of apoptosis in B and T lymphocytes which contributes to negative selection and the induction of immune tolerance.CD24 on antigen presenting cells cooperates with B7 molecules in the costimulation of T cells.CD24 associates in cis with Siglec10 and with the danger-associated molecules HMGB1，HSP70，or HSP90 which are released from necrotic or damaged cells.Formation of these ternary complexes fills a protective role: the resulting Siglec10 signaling inhibits inflammatory responses that are otherwise induced by extracellular DAMPs.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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