Recombinant Human BCMA/TNFRSF17/CD269/B cell maturation antigen,BR

产品属性 Product Attributes

基本信息

别名： Tumor necrosis factor receptor superfamily member 17;B-cell maturation protein;CD269;TNFRSF17;BCM;BCMA
中文名称: Recombinant Human BCMA/TNFRSF17/CD269/B cell maturation antigen
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： B cell maturation antigen (BCMA) is a member of the TNF receptor superfamily.It has been designated TNFRSF17.Human BCMA is a 184 amino acid (aa) protein consisting of a 54aa extracellular domain，a 23aa transmembrane domain，and a 107aa intracellular domain.BCMA is a type III membrane protein containing one extracellular cysteine rich domain.Within the TNFRSF，it shares the highest homology with TACI.BCMA and TACI have both been shown to bind to APRIL and BAFF，members of the TNF ligand superfamily.BCMA expression has been found in immune organs and mature B cell lines.Although some expression has been observed at the cell surface，BCMA appears to be localized to the Golgi compartment.The binding of BCMA to APRIL or BAFF has been shown to stimulate IgM production in peripheral blood B cells and increase the survival of cultured B cells.This data suggests that BCMA may play an important role in B cell development，function and regulation.
来源： P.Pichia

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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