Recombinant Mouse Folate Receptor Alpha/FOLR1,BR

产品属性 Product Attributes

基本信息

别名： Adult folate-binding protein;FBP;folate binding protein;folate receptor 1 (adult);Folate receptor 1;folate receptor alpha;Folate receptor,adult;Folbp1;FOLR;FOLR1;FR-alpha;KB cells FBP;MOv18;Ovarian tumor-associated antigen MOv18
中文名称: Recombinant Mouse Folate Receptor Alpha/FOLR1
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Folate Receptor alphabelongs to the folate receptor familyandit is a 37 - 42 kDa protein that mediates the cellular uptake of folic acid and reduced folates.Mature FOLR1 is an N-glycosylated protein that is anchored to the cell surface by a GPI linkage.FOLR1 can be detected in kidney proximal tubules.It is critically required during early embryogenesis as shown in knockout mice which die in utero with gross morphological defects.FOLR1 binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells.It Has high affinity for folate and folic acid analogs at neutral pH.Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release.Required for normal embryonic development and normal cell proliferation.Required for renal folate reabsorption.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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